Hypothalamic hormones a.k.a. hypothalamic releasing factors
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منابع مشابه
Hypothalamic hormones a.k.a. hypothalamic releasing factors.
Originally searched for and eventually isolated as factors of hypothalamic origin controlling anterior pituitary secretions, these hypophysiotropic peptides are now a chapter of physiology and medical endocrinology of their own. Defying the concept of 'neuropeptides' they and their receptors are now known to be ubiquitous and to have subtle as well as profound effects on a large number of funct...
متن کاملImmunohistochemical localization of hypothalamic hormones.
Using an immunoperoxidase technique at the light and electron microscope levels, the localization of somatostatin and luteinizing hormone-releasing hormone (LH-RH) has been performed in the brain, as well as the pancreas and stomach. The following generalizations may be drawn on the localization of LH-RH and somatostatin. (a) LH-RH and somatostatin are contained in axons and nerve endings of th...
متن کاملHypothalamic regulatory hormones: a review.
It has long been suggested that the secretion of the anterior pituitary hormones is under the control of the hypothalamus (Green and Harris, 1947; Harris, 1955). Early studies of the vasculature of the hypothalamic-hypophyseal system in birds and mammals described a portal system of capillaries in close contact with neurosecretory cells of the median eminence of the hypothalamus and draining to...
متن کاملPurification of anterior pituitary and hypothalamic hormones.
Pure preparations of pituitary and hypothalamic hormones are needed mainly for (1) their chemical characterisation, which increases our understanding of their biochemistry and makes their synthesis possible; (2) replacement therapy, in which contamination with other pituitary hormones is undesirable; and (3) the development of specific diagnostic assays. Pituitary hormones were first isolated f...
متن کاملModulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase.
Corticotropin-releasing hormone (CRH) and growth hormone-releasing hormone (GHRH), primarily characterized as neuroregulators of the hypothalamic-pituitary-adrenal axis, directly influence tissue-specific receptor-systems for CRH and GHRH in the endocrine pancreas. Here, we demonstrate the expression of mRNA for CRH and CRH-receptor type 1 (CRHR1) and of protein for CRHR1 in rat and human pancr...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2005
ISSN: 0022-0795,1479-6805
DOI: 10.1677/joe.1.05883